The wreck was cleared around 7:30 p.m. Friday.
Traffic is backed up on Interstate 81 North in Roanoke County because of a multiple-vehicle accident.
The accident is at mile marker 138.
Traffic is backed up about four miles.
VDOT says driver can expect "major delays."
The wreck on I-581 has been cleared.
A wreck on I-581 North in the City of Roanoke is also traffic.
That wreck is near Orange Avenue. Two lanes of northbound traffic are blocked, and one lane of southbound traffic is blocked.
There is also a concert tonight at the Roanoke Civic Center.