ROANOKE, Va.—
UPDATED: 11:20 a.m.
The Virginia Department of Transportation says the accident has been cleared and traffic is moving smoothly now.
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Interstate 81 South is backed up near the 143 mile marker in Roanoke. That's near the interchange with Interstate 581.
The south left lane is closed right now because of a multi-vehicle accident.
Traffic back-ups are about 6 miles.
