Week 12 College Football Computer Picks & Predictions

Looking for the best bet among all 63 Football Bowl Subdivision matchups in Week 12? Our choice, in terms of the point spreads, is Duke at -3 -- but scroll down, because we have plenty more suggestions, which could lead to parlay opportunities.

Get computer predictions and insights for that game and more in the article below.

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College Football Computer Picks - Best Spread Bets

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Pick: Duke -3 vs. Virginia

Matchup: Duke Blue Devils at Virginia Cavaliers
Projected Favorite & Spread: Duke by 13.8 points
Time: 3:00 PM ET
Date: November 18
TV Channel: The CW

Pick: Iowa -3 vs. Illinois

Matchup: Illinois Fighting Illini at Iowa Hawkeyes
Projected Favorite & Spread: Iowa by 13.7 points
Time: 3:30 PM ET
Date: November 18
TV Channel: Fox Sports 1
Live Stream: Fubo

Pick: New Mexico State +26.5 vs. Auburn

Matchup: New Mexico State Aggies at Auburn Tigers
Projected Favorite & Spread: Auburn by 16.1 points
Time: 4:00 PM ET
Date: November 18
TV Channel: SEC Network
Live Stream: Fubo

Pick: West Virginia -5.5 vs. Cincinnati

Matchup: Cincinnati Bearcats at West Virginia Mountaineers
Projected Favorite & Spread: West Virginia by 15.0 points
Time: 2:30 PM ET
Date: November 18
TV Channel: ESPN+
Live Stream: ESPN+

Pick: Florida International +28.5 vs. Arkansas

Matchup: Florida International Panthers at Arkansas Razorbacks
Projected Favorite & Spread: Arkansas by 19.0 points
Time: 7:30 PM ET
Date: November 18
TV Channel: ESPNU
Live Stream: Fubo

College Football Computer Picks - Best Total Bets

Over 30.5 - East Carolina vs. Navy

Matchup: East Carolina Pirates at Navy Midshipmen
Projected Total: 42.0 points
Time: 12:00 PM ET
Date: November 18
TV Channel: ESPNews
Live Stream: Fubo

Over 53.5 - Cal vs. Stanford

Matchup: California Golden Bears at Stanford Cardinal
Projected Total: 64.8 points
Time: 6:30 PM ET
Date: November 18
TV Channel: Pac-12 Network
Live Stream: Fubo

Under 73.5 - Georgia State vs. LSU

Matchup: Georgia State Panthers at LSU Tigers
Projected Total: 63.8 points
Time: 8:00 PM ET
Date: November 18
TV Channel: ESPN2
Live Stream: Fubo

Over 32.5 - Illinois vs. Iowa

Matchup: Illinois Fighting Illini at Iowa Hawkeyes
Projected Total: 42.1 points
Time: 3:30 PM ET
Date: November 18
TV Channel: Fox Sports 1
Live Stream: Fubo

Over 45 - Nevada vs. Colorado State

Matchup: Nevada Wolf Pack at Colorado State Rams
Projected Total: 54.3 points
Time: 3:00 PM ET
Date: November 18
TV Channel: MW Network
Live Stream: Fubo

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